Effect of early tracheal intubation on hypoxemia and level of blood lactate, C-reactive protein in patients with severe intracerebral hemorrhage
- VernacularTitle:早期气管插管对重症脑出血患者的低氧血症及血乳酸、C反应蛋白水平的影响
- Author:
Tao WANG
;
Lixin LIU
;
Yuanhui WEI
- Publication Type:Journal Article
- Keywords:
intracerebral hemorrhage;
tracheal intubation;
lactate;
C-reactive protein
- From:
Journal of Clinical Neurology
2014;(3):225-227
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of early tracheal intubation on hypoxemia and level of blood lactate, C-reactive protein(CRP) in patients with severe intracerebral hemorrhage .Methods Fifty-four patients with severe intracerebral hemorrhage were divided into routine tracheal intubation (routine intubation group,n=25) and early tracheal intubation group(early intubation group,n=29) radomly.In routine tracheal intubation group, tracheal intubation was performed only when respiratory failure occurred .In early intubation group , tracheal intubation was performed as long as hypoxemia which can not be fixed by inspiring oxygen , tongue retropulsion or vomit occurred . Levels of artery blood gas analysis , lactate and CRP were tested before and after 2 h ( lactate ) or 24 h ( CRP ) of tracheal intubation .Heart rate and respiratory frequency were also monitored .Results PaO2 , PaCO2 , SaO2 and heart rate were markedly improved after intubation in both groups , levels of lactate and CRP were evidently reduced after intubation in both groups(all P<0.05).After intubation, the PaO2 of early intubation group was significantly higner and the CRP of early intubation group was significantly lower than that of routine intubation group ( all P<0.05);Before intubation, the PaO2 and SaO2 of early intubation group were significantly higher and levels of lactate and CRP were significantly lower than those of routine intubation group ( P<0.05 ) .Conclusion Early tracheal intubation can improve hypoxemia and reduce the level of lactate and CRP in patients with severe intracerebral hemorrhage .
