Study on the risk factors for coronary artery lesions in children with Kawasaki disease in Lanzhou

VernacularTitle:兰州地区川崎病患儿并发冠状动脉损害的危险因素研究
Author: Lin ZHU ; Shaomin NIU ; Xiangyu DONG ; Yinan YANG ; Qian NI
Publication Type:Journal Article
Keywords: Kawasaki disease; coronary artery lesions; risk factors; child
From: Journal of Clinical Pediatrics 2014;(7):616-619
CountryChina
Language:Chinese
Abstract: Objective To investigate the risk factors for coronary artery lesions (CALs) in children with Kawasaki disease (KD) in Lanzhou. Methods One hundred and seventy-four children with diagnosed KD were divided into CAL group and non-CAL group based on the existence of concurrent CALs. The age, gender, fever duration, intravenous immunoglobulin (IVIG) start time, IVIG dose, C-reactive protein (CRP), serum albumin, erythrocyte sedimentation rate (ESR), platelet (PLT), red blood cell count (RBC), hemoglobin and so on were compared. Results Among the 174 children, 46 children (26.44%) were complicated by CALs and 128 children were not. The differences of average fever duration, IVIG starting time, IVIG dose, PLT, CRP, ESR and RBC were statistically signiifcant (P<0.05). Conclusions When KD children has the fever durations>10 d, start of IVIG af-ter 10 days of fever, increase of PLT, CRP and ESR and decrease of RBC, clinicians should be alert to the risk of concurrent CAL.