Mammographic features and pathological characteristics among different molecular subtypes of breast cancer
10.3969/j.issn.1002-1671.2014.07.017
- VernacularTitle:不同分子亚型乳腺癌X线征象及病理特征分析
- Author:
Xiaoyan LIANG
;
Xiaoli KANG
;
Jing QIN
;
Tao WANG
;
Ying HUANG
;
Minyi FAN
;
Hui LIU
- Publication Type:Journal Article
- Keywords:
breast cancer;
molecular subtypes;
mammography
- From:
Journal of Practical Radiology
2014;(7):1133-1136
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the mammographic features and pathological characteristics among different molecular subtypes of breast cancer.Methods The results of 210 cases breast cancer identified by postoperative pathology were collected and classified to three groups;Luminal,HER-2(+)and TNBC(triple negative breast cancer)by molecular subtypes.Three groups'mammograph-ic features and pathological characteristics were compared.Results 210 cases included 147 Luminal cases,30 HER-2 (+)cases and 33 TNBC cases.There were statistically significant difference between tumor grading and lymph node metastasis (P <0.05).Three groups had statistically significant difference among mass number,mass margin and calcification incidence(P <0.05),and had no sta-tistically significant difference between mass size and shape(P >0.05).The mammographic features of Luminal molecules subtypes showed more mass with burr,HER-2(+)molecules subtypes showed no fixed features but more calcification incidence than other groups,TNBC molecules subtypes showed merely mass with clear margin and less calcification.Conclusion The mammographic fea-tures and pathological characteristics of different molecular subtypes of breast cancer are significant differences.
