The value of DWI based on biexponential model in differential diagnosis of benign and malignant breast lesions
10.3969/j.issn.1002-1671.2014.07.018
- VernacularTitle:双指数模型 DWI在乳腺良恶性病变鉴别诊断中的价值
- Author:
Jie HE
;
Yan ZHANG
;
Jingliang CHENG
;
Ying HU
;
Anfei WANG
- Publication Type:Journal Article
- Keywords:
diffusion weighted imaging;
breast tumor;
biexponential signal decay
- From:
Journal of Practical Radiology
2014;(7):1137-1140
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application value of DWI based on biexponential signal decay model with extended b-fac-tor range in differential diagnosis of benign and malignant breast lesions.Methods A total of 57 patients with breast tumor under-went DWI based on the biexponential model with 12 b-factors (0,10,20,50,100,200,400,600,800,1000,1 200 and 1 500 s/mm2 ), including benign lesions in 1 9 patients (24 breast tumors,defined as benign group)and malignant ones in 38 (47 tumors,defined as malignant group ).The values of slow apparent diffusion coefficient,fast apparent diffusion coefficient and fraction of fast ADC of le-sions were measured at a workstation (Advantage Windows 4.5).Differences in these parameters between the benign and malignant groups were compared.Results The ADCslow,ADCfast and ffast were(1.434±0.291)×10 -3 mm2/s,(2.744±0.050)×10 -3 mm2/s and (0.677±0.130)% in benign group,and (0.614±0.196)×10 -3 mm2/s,(2.692±0.068)×10 -3 mm2/s and (0.446±0.112)% in malig-nant one,respectively.The statistical differences in ADCslow and ffast were found between two groups (P <0.05),whereas no difference in ADCfast was found.Conclusion Biexponential signal decay model of DWI with extended b-factor range can provide helpful tissue characterization parameters for the differential diagnosis of benign and malignant breast lesions.
