Study on Composition of Drug Property of Hot-natured Herb Euodiae Fructus
10.3969/j.issn.1005-5304.2014.07.023
- VernacularTitle:热性中药吴茱萸药性成分研究
- Author:
Yihui XIE
;
Yutian ZHANG
;
Jinrong LUO
;
Liping HUANG
- Publication Type:Journal Article
- Keywords:
Euodiae Fructus;
cold syndrome;
energy metabolism;
herbal nature;
rats
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(7):77-80
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the material basis of hot-natured herb Euodiae Fructus. Methods Euodiae Fructus extract was separated into the chloroform fraction, ethyl acetate fraction, n-butanol fraction and water fraction. With cold syndrome rat model by reserpine, the study confirmed that n-butanol fraction of Euodiae Fructus has influence on energy metabolism in rats. With the modified magnetic polymer microspheres, Euodiae Fructus n-butanol was divided into alkaloids, phenolic acid, fat soluble and water-soluble components, and the component of Euodiae Fructus influencing energy metabolism of model rats was further confirmed.Results The Euodiae Fructus extracts and alkaloids elevated rats temperature, reduced the Na+-K+-ATP activity, increased SDH activity, the content of ATP in liver tissue, the energy charge (EC) value and body heat production, and improve the level of energy metabolism.Conclusion The alkaloid is the material basis of hot-natured herb Euodiae Fructus.
