Relationship Between the Ambulatory Arterial Stiffness Index and Left Ventricular Mass Index, Left Atrial Diameter in Patients With Hypertension
10.3969/j.issn.1000-3614.2014.06.012
- VernacularTitle:高血压患者动态动脉硬化指数与左心室质量指数、左心房内径的相关性分析
- Author:
Yuqin LU
;
Yingdong LI
;
Xinke ZHAO
- Publication Type:Journal Article
- Keywords:
Hypertension;
Arterial stiffness index;
Left ventricular mass index;
Left atrial diameter
- From:
Chinese Circulation Journal
2014;(6):440-443
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the relationship between ambulatory arterial stiffness indexes (AASI), AASI-blood pressure variability (AASI-BPVR) and left ventricular mass index (LVMI) left atrium diameter (LAD) in patients with hypertension.
Methods: A total of 286 hypertensive patients were enrolled in this study. The AASI, AASI-BPVR were calculated from 24-hour ambulatory blood pressure monitoring. Left ventricular internal dimension in diastole (LVIDd), interventricular septal thickness in diastole (IVSd), posterior wall thickness in diastole (PWd), LAD were detected by echocardiography and LVMI, relative wall thickness (RWT) were calculated. The fasting blood glucose, blood lipids were examined. According to 24 h AASI, the patients were divided into 2 groups, Group A, the patients with AASI > 0.51, n=133 and Group B, the patients with AASI ≤ 0.51,n=153. Pearson and multi regression analysis were conducted to analyze the relevant correlations.
Results: Group A had increased LVMI than that in Group B,P<0.05, the left ventricular masses were similar between 2 groups,P=0.384. Pearson correlation analysis indicated that LVMI and LAD were not related to arterial stiffness index, the coefifcient between 24 h-AASI and LAD was atr=0.111,P=0.057.
Conclusion: AASI and AASI-BPVR were not the independent factors for left ventricular hypertrophy and left atrial enlargement, therefore, they were not the predictors for cardiac damage in patients with hypertension at present time.
