Research progress of regulatory T cells in gastric cancer
10.3760/cma.j.issn.1006-9801.2014.06.021
- VernacularTitle:调节性T细胞在胃癌中的研究进展
- Author:
Xiaojuan YANG
- Publication Type:Journal Article
- Keywords:
Gastric neoplasms;
Regulatory T cells;
Immunotherapy
- From:
Cancer Research and Clinic
2014;26(6):428-430
- CountryChina
- Language:Chinese
-
Abstract:
Regulatory T cells are a group of subgroup T cells with special immune regulating function,which participate in keeping immune homeostasis and play important roles in preventing autoimmune diseases.However,regulatory T cells also promote tumor immune evasion.The highly increase of its expression will significantly reduce the smvival rate of cancer patients.Gastric cancer with high mortality is difficult to detect in early stage.China is one of the high-prevalence gastric cancer countrys.This article mainly introduced the sources,classification and immune phenotype of regulatory T cells and its function mechanism to explore its relationship with gastric cancer in order to discover the new strategy of tumor immunotherapy.
