The correlation of leptin, IGF-1 and adiponectin in fetal cord blood with intrauterine growth retardation
10.3760/cma.j.issn.1008-6706.2014.13.022
- VernacularTitle:胎儿宫内发育迟缓与胎儿脐血瘦素、胰岛素样生长因子-1和脂联素的相关性研究
- Author:
Yaqin LI
- Publication Type:Journal Article
- Keywords:
Intrauterine growth retardation;
Leptin;
Insulin-like growth factor-1;
Adiponectin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;21(13):1972-1973
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation of leptin,insulin-like growth factor-1 (IGF-1) and adiponectin in fetal cord blood with intrauterine growth retardation (IUGR).Methods Sixty-one fetus with IUGR were enrolled into the observation group and eighty healty fetus were enrolled into the control group.Leptin,IGF-1 and adiponectin were detected.Results The levels of leptin,IGF-1 and adiponectin in the observation group were lower than those in the control group,there were significant differences between the two groups (t =11.239,11.680,13.640,all P < 0.01).The body mass in the observation group was (2 157 ± 243) g,which had significantly positive correlation with leptin (r =0.274,P < 0.05),IGF-1 (r =0.532,P < 0.05) and adiponectin (r =0.539,P < 0.05).Conclusion There was a close relationship in leptin,IGF-1 and adiponectin with IUGR.