The correlation of leptin, IGF-1 and adiponectin in fetal cord blood with intrauterine growth retardation

VernacularTitle:胎儿宫内发育迟缓与胎儿脐血瘦素、胰岛素样生长因子-1和脂联素的相关性研究
Author: Yaqin LI
Publication Type:Journal Article
Keywords: Intrauterine growth retardation; Leptin; Insulin-like growth factor-1; Adiponectin
From: Chinese Journal of Primary Medicine and Pharmacy 2014;21(13):1972-1973
CountryChina
Language:Chinese
Abstract: Objective To study the correlation of leptin,insulin-like growth factor-1 (IGF-1) and adiponectin in fetal cord blood with intrauterine growth retardation (IUGR).Methods Sixty-one fetus with IUGR were enrolled into the observation group and eighty healty fetus were enrolled into the control group.Leptin,IGF-1 and adiponectin were detected.Results The levels of leptin,IGF-1 and adiponectin in the observation group were lower than those in the control group,there were significant differences between the two groups (t =11.239,11.680,13.640,all P ＜ 0.01).The body mass in the observation group was (2 157 ± 243) g,which had significantly positive correlation with leptin (r =0.274,P ＜ 0.05),IGF-1 (r =0.532,P ＜ 0.05) and adiponectin (r =0.539,P ＜ 0.05).Conclusion There was a close relationship in leptin,IGF-1 and adiponectin with IUGR.