Retrospectively analyze 27 cases of death in AIDS patients with Penicilliosis marneffei
10.3969/j.issn.1006-5725.2014.13.031
- VernacularTitle:艾滋病合并马尔尼菲青霉病死亡病例27例回顾性分析
- Author:
Jiansheng ZHANG
;
Wenxin HONG
;
Linghua LI
;
Xiaoping TANG
;
Xiejie CHEN
- Publication Type:Journal Article
- Keywords:
Acquired immunodeficiency syndrome;
Penicilliosis;
Mortality;
Clinical characters analysis
- From:
The Journal of Practical Medicine
2014;(13):2108-2110
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characters of death in AIDS patients with Penicilliosis marneffei (PSM), improving the diagnosis and treatment of PSM. Methods Retrospectively analyze the data of 27 AIDS patients died of PSM from January 2009 to December 2011 and review the relevant literatures in the past several years. Results The etiology diagnosis time ranged from 4 to 7 (4.9 ± 1.4) days from admission. There were 22 (81.5%) cases complicated with septic shock and 25 (92.6%) cases complicated with metabolic acidosis. There were 12 (44.4%) cases co-infected with pneumocyst pneumonia , 7 (25.9%) cases with TB. The main reasons accounting for the death were as follow:15(55.6%) cases died of septic shock, 5(18.5%) cases died of respiratory failure. Conclusion The death cases of AIDS patients with PSM showed the characters of relatively late etiology diagnosis and pathogenic therapy , mostly complicated with other opportunistic infections and often died of septic shock. Therefore, timely etiology diagnosis and earlier pathogenic therapy are the keys to treat the disease. Effectively controlling of the complications and co-infections may decrease the mortality.
