Retrospective analysis the effect of linezolid on severe Gram-positive bacteria infection in children
10.3969/j.issn.1000-3606.2014.06.015
- VernacularTitle:利奈唑胺治疗儿童重症革兰阳性菌感染的回顾性分析
- Author:
Seyiti JUAITI
;
Yunzhi CUI
;
Muzhapaer DUOLIKUN
- Publication Type:Journal Article
- Keywords:
linezolid;
severe infections;
Gram positive bacteria;
child
- From:
Journal of Clinical Pediatrics
2014;(6):559-561
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of linezolid on severe Gram-positive bacteria infection in chil-dren. Methods The retrospective analysis was performed in the clinical cases of severe Gram-positive bacteria infection which were insensitive to drugs selected from experience but sensitive to linezolid according to sputum culture and sensitivity test. Re-sults Twenty-four children with severe Gram-positive bacterial infections were treated with linezolid by intravenous infusion (10 mg/kg, q8h) for 10-14 days. All of them were markedly improved. Conclusions When drugs selected from experiences are ineffective, linezolid or in combination with other drugs is a good choice in the treatment of severe Gram-positive bacterial in-fections.
