MRI in the differential diagnosis of breast ductal cancer in situ

VernacularTitle:MRI鉴别乳腺导管原位癌与其他导管内病变的价值
Author: Chao YOU ; Yajia GU ; Weijun PENG ; Jian MAO ; Tingting JIANG
Publication Type:Journal Article
Keywords: Breast; Ductal carcinoma in situ; MRI; Diagnosis
From:China Oncology 2014;(6):463-468
CountryChina
Language:Chinese
Abstract: Background and purpose: Ductal carcinoma in situ (DCIS), is precursor lesions of invasive breast cancer, belongs to non-systemic ductal lesions, which is similar to other ductal lesions on imaging. This study aimed to investigate the differential diagnostic value of MRI in DCIS between DCIS with microinvasion (DCIS-MI) and breast intraductal papilloma (BIDP). Methods:All the cases were surgico-pathologically conifrmed. Twenty-four patients were DCIS, 9 patients were DCIS-MI, and 20 patients were BIDP. The MRI charateristics of DCIS, DCIS-MI and BIDP were analyzed and compared. Results:DCIS and DCIS-MI’s performance in the form of MRI is dififcult to differentiate (P<0.05). Compared with BIDP, the ductal and segmental enhancement, typeⅢtime-signal intensity curve (TIC), and the red pseudo-color image were associated with the DCIS. The local area enhancement, typeⅡTIC, and no-red pseudo-color image were associated with BIDP. Conclusion:MRI is a useful for differentiate between DCIS and BIDP, but is dififcult for DCIS and DCIS-MI.