The effect of hyperthermia on spatial working memory:an fMRI study
10.3969/j.issn.1002-1671.2014.06.001
- VernacularTitle:高温负荷对空间工作记忆的影响--功能磁共振研究
- Author:
Qingjun JIANG
;
Xiao YANG
;
Kai LIU
;
Bo LI
;
Li LI
;
Min LI
;
Shaowen QIAN
;
Lifei MA
;
Gang SUN
- Publication Type:Journal Article
- Keywords:
hyperthermia;
functional magnetic resonance imaging;
spatial working memory
- From:
Journal of Practical Radiology
2014;(6):897-900
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of different brain regions of the human beings during completion of spatial working memory tasks under hyperthermia condition with functional magnetic yesonance.Methods Twenty-eight right-handed healthy young male volunteers were divided into control group and hyperthermia group randomly,and working memory task using block design was performed during behavioral test and fMRI scanning on both conditions.Activation intensity and location of different brain areas were compared in control and hyperthermia group.Results The activations of frontal,parietal,occipital and insular lobe were seen in both of the control group and the hyperthermia group.Right lateralization was shown in control group during spatial working memory (Li=0.05 1).While,in hyperthermia group the effect of the right lateralization significantly was enhanced (Li=0.103). Moreover,activation of bilateral middle frontal gyrus and right parietal lobe were significantly enhanced.Conclusion It is found for the first time that the hyperthermia could affect bilateral middle frontal gyrus and right parietal lobe,and enhance the effect of right lateralization in the spatial working memory task.
