Radiosensitivity and Dose-urvival Characteristics of Crypt Cells of Mouse Jejunum.
- Author:
Seoung Jae HUH
1
;
Charn Il PARK
Author Information
1. Department of Radiology, College of Medicine, Soonchunhyang University, Korea.
- Publication Type:Original Article
- MeSH:
Animals;
Cesium;
Jejunum*;
Mice*;
Radiation Tolerance*
- From:Journal of the Korean Society for Therapeutic Radiology
1985;3(1):9-12
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To determine the radiosensitivity and dose-urvival characteristics of jejunal crypt cells, experimental study was done using total 40 mice. Single irradiation of 1,000rad to 1,600rad was delivered to whole bodies of mice, using a cesium 137 animal irradiator. The number of regenerating crypts per jejunal circumference was counted, by using a jejunal crypt cell assay technique, and dose response curve was measured. The average number of jejunal crypt per circumference in control group was 140+/-10. Mean lethal dose(D0) of mouse jejunal crypt cell was 135rad.
