Clinical diagnosis and analysis of primary pulmonary mucosa-as-sociated lymphoid tissue lymphoma:A report of seven cases
10.3969/j.issn.1000-8179.20131268
- VernacularTitle:肺黏膜相关淋巴组织样淋巴瘤7例并临床诊断与分析
- Author:
Sida PENG
;
Huo TAN
;
Zhenqian HUANG
;
Runhui ZHENG
;
Pengfei QIN
;
Juhong JIANG
- Publication Type:Journal Article
- Keywords:
pulmonary;
lymphoma;
mucosa-associated lymphoid tissue;
diagnosis
- From:
Chinese Journal of Clinical Oncology
2014;(14):922-924
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study aims to examine the clinicopathological features, diagnosis, and treatment of pulmonary margin-al zone B-cell lymphoma of mucosa-associated lymphoid tissue (PMZL-MALT). Methods:The clinicopathological features and immu-nohistochemical staining of CD20, CD79a, CD5, CD10, CD23, CyclinD1, and Ki-67 in seven patients with PMZL-MALT were ana-lyzed. Results:These patients, with a median age of 58 years, included three males and four females. Most of the patients suffered from cough, anhelation, and irregular fever. No specific imaging manifestation was observed. Tumor cells were positive for CD19 and CD20 but negative for CD5, CD10, and CyclinD1. The positive rate of Ki-67 was low. Conclusion:PMZL-MALT cases are easily misdiag-nosed because of the absence of specific clinical characteristics and X-ray features. Final diagnosis depends on pathological examina-tions.