Anti-aging function of placenta freeze-dried powder on mice
- VernacularTitle:胎盘冻干粉对小鼠延缓衰老作用的研究
- Author:
Hang SONG
;
Chuanbao ZANG
;
Xiaodun LIU
;
Huaishui HOU
;
Dong LI
- Publication Type:Journal Article
- Keywords:
placenta freeze-dried powder;
D-galactose;
anti-aging
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;(1):65-67
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate Anti-aging function of Placenta freeze-dried powder on mice. Method 2 month old female-KM mice were divided into five groups:normal control group, aging model group, positive control group, placenta freeze-dried powder low dose group and high dose group. Except normal control group,the rest of groups were treated with method of subcutaneous continuous injection of D-galactose for 42 days in order to establish mice aging model. Meanwhile, the corresponding drugs, via intragastric administration, were ingested by different treated groups and observe the change of immunity and physiological regulation related in mice. Results Compared with aging model group, thymus index and spleen index in placenta freeze-dried powder low dose group and high dose group increased obviously (P<0.05), content of MDA in brain decreased significantly (P<0.05), proportion of CD 4 and CD 8 lymphocyte in total lymphocyte, female hormone(P and E 2), IgG and haemopoietic factor in peripheral blood increased remarkably. Conclusion Placenta freeze-dried powder could slow the aging process on mice via immunity enhancement and improving physical regulation.
