The In Vivo and In Vitro research status and future prospects of HPMC capsules
- VernacularTitle:HPMC胶囊的体内外研究现状与应用展望
- Author:
Xiyao ZHANG
;
Yonglu WANG
;
Dong WANG
;
Xueming LI
- Publication Type:Journal Article
- Keywords:
HPMC capsule;
in vivo and in vitro research;
disintegration;
bioavailability;
pharmacokinetics
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;(1):138-141
- CountryChina
- Language:Chinese
-
Abstract:
After a literature review of the HPMC capsules, the research status of the HPMC capsules in vivo and in vitro are summarized, including the application status, the superiority over hard gelatin capsules and in particularly the disintegration release in vitro and bioavailability in vivo, as well as pharmacokinetics difference compared with conventional gelatine capsules, are explored in depth. Finally, the future applications of HPMC capsules are prospected.
