Role of the AhR ligand in the development of tumor
- VernacularTitle:芳香烃受体的配体在肿瘤发生发展中的作用
- Author:
Jianxin ZHANG
;
Liping XU
;
Fuhou CHANG
;
Tuya BAI
;
Xiaoli LV
;
Feng GAO
- Publication Type:Journal Article
- Keywords:
aryl hydrocarbon receptor;
ligand;
agonists;
antagonists;
tumor
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;(1):150-152
- CountryChina
- Language:Chinese
-
Abstract:
Aryl hydrocarbon receptor (AhR) is a ligand-dependent activation of transcription factor, which is activated by a large variety of ligands, resulting in the expression of metabolic enzymes and a series of downstream gene activation, and closely related with tumor development . Now a review for AhR ligands with different structural and functional and its relationship with tumor, in order to provide a new target for tumor therapy.
