Plasma IL-37 levels in patients with acute coronary syndrome
10.3969/j.issn.1006-5725.2014.10.013
- VernacularTitle:急性冠脉综合征患者血浆IL-37水平变化及意义
- Author:
Ying HUANG
;
Yingzhong LIN
;
Ying SHI
;
Zhengde LU
;
Ling LIU
;
Xiaoyan WANG
;
Qingwei JI
- Publication Type:Journal Article
- Keywords:
Acute coronary syndrome;
IL-37;
Inflammation
- From:
The Journal of Practical Medicine
2014;(10):1559-1561
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of plasma IL-37 levels in patients with acute coronary syndrome (ACS). Methods Plasma biomarkers IL-37, CRP and NT-proBNP levels were measured in 40 patients with stable angina pectoris (SA group), 65 patients with unstable angina pectoris (UA group), 47 patients with acute myocardial infarction (AMI group) and 60 control patients. Results The plasma IL-37, CRP and NT-proBNP levels were significantly increased in patients with ACS patients. A correlation analysis showed that the plasma IL-37 levels were positively correlated with the levels of CRP and NT-proBNP, and negatively correlated with LVEF. Conclusions The results indicated that the plasma IL-37 levels are associated with the onset of ACS symptoms.
