Application of strong ion gap and other indicators in ICU

VernacularTitle:强离子隙等指标在 ICU 中的应用探讨
Author: Zhongyuan ZHANG ; Wangping HU ; Xidi CHI ; Guiyun YE ; Shanghua XU ; Yongping ZHANG ; Longfei YE
Publication Type:Journal Article
Keywords: strong ion gap; intensive care units; blood gas analysis; lactic acid
From: International Journal of Laboratory Medicine 2014;(13):1683-1685
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical application value of strong ion gap(SIG)generated by the third generation equa-tion following pH and the anion gap(AG)in critically ill patients.Methods On the basis of the determination results of blood gas and blood biochemistry,the equation in the Stewart-Figge methodology was adopted to calculate SIG.Results (1)There were sta-tistically significant differences in K+ ,Na+ ,HCO3 - ,AG,pH,PO4 3 - ,ALB,SIG and Cr between the critical illness groups and the control group(P <0.05).(2)The SIG mean value ratio the death group to non-death group was 3.04,the difference was the big-gest,P <0.05,AG and Cr took the second place.Conclusion SIG as a new indicator in combination with other biochemical and blood gas indicators,such as the HCO3 - ,AG,pH,PO4 3 - ,Cr and lactic acid can reflect the situation of the acid-base disorders in critically ill patients and plays a strong indicative role in predicting the disease development trends.