Value of modified Ziehl-Neelsen acid-fast staining of bronchoalveolar lavage fluid in diagnosis of pulmonary tuberculosis with negative sputum
10.3969/j.issn.1673-4130.2014.13.015
- VernacularTitle:支气管镜肺泡灌洗液改良抗酸染色法诊断菌阴性肺结核的价值探讨
- Author:
Jiping ZHANG
;
Xiaojin LIU
;
Yingbin YE
;
Xiuxiang HUANG
;
Liheng ZHENG
- Publication Type:Journal Article
- Keywords:
fiberoptic bronchoscope;
tuberculosis,pulmonary;
bronchoalveolar lavage fluid
- From:
International Journal of Laboratory Medicine
2014;(13):1702-1703
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the modified Ziehl-Neelsen acid -fast staining method and to investigate the value of modi-fied Ziehl-Neelsen acid-fast staining method of bronchoalveolar lavage fluid in the diagnosis of pulmonary tuberculosis(TB)with negative sputum specimen.Methods 50 cases of negative sputum pulmonary TB were performed the bronchoalveolar lavage by the fiberoptic bronchoscope before the treatment,at the same time,the bronchoalveolar lavage fluids were collected and detected by the two methods of the traditional and modified Ziehl-Neelsen staining.The diagnostic positive rates were compared between the two groups.Results The positive rates of the two kinds of acid-fast staining method were 38% and 82% respectively,the difference showing statistical significance(P <0.05 ).Conclusion The modified Ziehl-Neelsen acid-fast staining of bronchoalveolar lavage fluid can highly improve the positive diagnostic rate of pulmonary TB patients with negative sputum and deserves to be clinically promoted.
