Application of nucleic acid test in voluntary blood donors in Hefei area
10.3969/j.issn.1673-4130.2014.13.033
- VernacularTitle:合肥地区无偿献血者核酸检测的应用研究
- Author:
Youhong DUAN
;
Weifang CHENG
;
Haiping MENG
;
Jingjing MA
- Publication Type:Journal Article
- Keywords:
nucleic acid test;
enzyme-linked immunosorbent assay;
blood screening
- From:
International Journal of Laboratory Medicine
2014;(13):1742-1744
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the role of nucleic acid test(NAT)in blood screening to provide the scientific basis for the se-lection of blood screening strategies.Methods The serological detection and NAT were simultaneously performed on 68 662 speci-mens of voluntary blood donation from January 2012 to April 2013;29 samples of HBV DNA positive with serological HBsAg nega-tive were performed the serum HBV markers detection.Partial samples of anti-HIV antibody positive were sent to CDC for conduc-ting the confirmation test.Results Among 68 662 samples,120 cases of single NAT positive were detected out,the residual risk of blood transfusion was 0.175%.In the serum HBV markers detection,the mode of HBcAb was predominant.11 cases of HIV posi-tive were confirmed and all were the NAT positive samples.Conclusion NAT can reduce the residual risk of blood transfusion,en-sure the safety of blood transfusion.NAT and the serological detection are mutual complementation and not replaced by each other. The suitable screening strategy shold be selected.
