Association between HCV-RNA and chemiluminescence immunoassay for detecting anti-HCV antibody
10.3969/j.issn.1673-4130.2014.13.036
- VernacularTitle:化学发光免疫分析检测抗-HCV 抗体与 HCV-RNA 的关联研究
- Author:
Yiqing LIU
;
Jianwen ZOU
;
Wenjun TIAN
;
Chunmei LIU
;
Shenghua WANG
;
Yong WANG
;
Yueran ZHAO
;
Bingchang ZHANG
- Publication Type:Journal Article
- Keywords:
hepatitis C antibodies;
chemiluminescent measurements;
polymerase chain reaction
- From:
International Journal of Laboratory Medicine
2014;(13):1749-1750
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlation of real-time fluorescent quantitation PCR(FQ-PCR)for detecting HCV-RNA loading and the chemiluminescence immunoassay(CLIA)for detecting anti-HCV antibody.Methods 587 samples of anti-HCV an-tibody positive detected by CLIA were furteher detected HCV-RNA by FQ-PCR.Results Among 587 samples of anti-HCV anti-body positive by the CLIA screening,225 samples were HCV-RNA negative and 362 samples were HCV-RNA positive detected by FQ-PCR,and the positive rate was 61 .67%,moreover,which was positively correlated with the S/CO ratio detected by CLIA.Con-clusion The positive rate of HCV-RNA is positively correlated with the S/CO ratio detected by CLIA.The result of HCV-RNA can be predicted according to the S/CO ratio.
