Exploration on Curative Effect of Zhuo-Du-Qing Particles on Diabetic Cystopathy Based on Theory of Turbid Toxin
10.11842/wst.2014.06.019
- VernacularTitle:基于浊毒理论探讨浊毒清颗粒对糖尿病性膀胱的疗效
- Author:
Wei ZHAO
;
Xiaotao FENG
;
Shuanglei LI
;
Linna ZHAI
;
Zhengang WANG
;
Rong HUANG
;
Wenhui CHEN
;
Min LI
;
Feng LUO
;
Chunli TANG
;
Yan QIN
- Publication Type:Journal Article
- Keywords:
Zhuo-Du-Qing;
turbid toxin;
toxin-removing and turbid-descending;
diabetic cystopathy;
clinical observation
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2014;(6):1313-1317
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to explore the curative effect of Zhuo-Du-Qing (ZDQ) particles on diabetic cystopa-thy (DCP) based on the theory of turbid toxin. A total of 100 DCP patients were randomly divided into the control group with 47 cases and the treatment group with 53 cases. Mecobalamin tablets was given in the control group. And ZDQ particles were given to the treatment group. The treatment course was 3 months. The observation was made on the bladder residual urine (BRU), clinical manifestation integral, hemodynamic indexes, HOMA-IR and HbA1c before and after the treatment. The results showed that compared with pretreatment, the BRU, clinical manifestation integral, hemodynamic indexes, and HOMA-IR were significantly reduced (P < 0.01). Compared with the control group, the BRU, clinical manifestation integral, hemodynamic indexes, and HOMA-IR were also significantly reduced (P <0.01). The effective rate in the treatment group was 81.1%, which was significantly higher than 59.6% in the control group (P< 0.05). There were no obvious changes on the blood routine examination, urine routine examination, stool routine examination, liver function, renal function, electrocardiogram and so on before and after treatment. It was con-cluded that the treatment of DCP with ZDQ particles was safe and effective. To remove toxin and descend turbid may be another effective treatment method for DCP. The occurrence and development of DCP were closely related to the turbid toxin.
