Research progress of Th22 and IL-22 in inflammatory skin disorders
10.3969/j.issn.1001-1978.2014.07.005
- VernacularTitle:Th22细胞及其效应因子IL-22与炎症性皮肤病关系的研究进展
- Author:
Liming ZHANG
;
Yaoyao DUAN
;
Xiaoqing DONG
;
Yanxin REN
;
Tan LI
;
Hong CHEN
- Publication Type:Journal Article
- Keywords:
Th22;
IL-22;
psoriasis;
atopic dermatitis;
systemic lupus erythematosus;
systemic sclerosis
- From:
Chinese Pharmacological Bulletin
2014;(7):905-907
- CountryChina
- Language:Chinese
-
Abstract:
Th22,a new subset of helper T cells,which is char-acterized by the secretion of interleukin-22(IL-22),could infil-trate to the epidermis in individuals with inflammatory skin disor-ders.This article introduces the action of Th22 and IL-22 in in-flammatory skin diseases,including psoriasis,atopic dermatitis, systemic lupus erythematosus,systemic sclerosis,aiming at re-vealing the role of Th22 and IL-22 in these diseases,which would not only provide some novel targets of drugs for inflamma-tory skin diseases,but also promote the researches on the pre-vention and treatment of these diseases.
