Surgical management of ectopic hyperparathyroidism: report of 66 cases

VernacularTitle:异位甲状旁腺功能亢进症的外科治疗——66例报告
Author: Heng GUAN ; Pei LI ; Yu ZHU ; Quan LIAO
Publication Type:Journal Article
Keywords: Hyperparathyroidism; Hormones,ectopic; Parathyroidectomy
From: Chinese Journal of General Surgery 2014;29(6):455-459
CountryChina
Language:Chinese
Abstract: Objective To discuss the features and surgical management of ectopic hyperparathyroidism.Methods Clinical data of 66 cases of ectopic hyperparathyroidism were retrospectively analyzed.Results There were 66 cases of ectopic hyperparathyroidism accounting for 11.5％ (66/575) of all ectopic hyperparathyroid cases admitted during the period from 1982-2010.Prevalence of mediastinal ectopic lesions was 71.2％ (47/66),among those 65.2％ (42/66) was in anterosuperior mediastinum,and 28.8％ (19/66) in the non-typical loci of the neck.Radionuclide imaging of parathyroid glands was the most sensitive (87.0％) method among all common positioning examinations.Average number of operation episode was 1.47,and all lesions were finally resected.After surgery 49 cases presented with transient hypocalcemia,and were cured by calcium administration.52 cases were followed up,with recurrent hyperparathyroidism in 1 case.Conclusions Diagnosis and treatment of ectopic hyperparathyroidism are dependent on the understanding of common locations of ectopic parathyroid glands.Preoperative correct location and surgical expertise are helpful for successful resection.