The myocardial protection of coen zyme compel x in patients with VR
- VernacularTitle:注射用复合辅酶对心脏瓣膜置换患者围术期的心肌保护作用
- Author:
Xiaogang GUO
;
Dong PENG
;
Sheng WANG
;
Sha LUO
- Publication Type:Journal Article
- Keywords:
Coenzyme complex;
Cardiopulmonary bypass;
Valve replace;
Protection of myo-cardial
- From:
Journal of Chinese Physician
2010;(z2):20-21
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate effection of the myocardial protective in treatment of coenzyme complex to the VR patients .Methods Eighty patients who need to VR were divided into control group ( n=40) and coenzyme complex group ( n =40) with double -blind.The automatic recovery rate of heart beats after cardiac resuscitation , the changes of postoperative arrhythmia rate , postoperative serum CK-MB, cTnI in 12h in two groups were recorded .Results The automatic recovery rate of heart beats was higher in coenzyme complex group than that in control group , (85%vs 67%, P <0.05).The changes of postopera-tive arrhythmia rate (26%vs 38%), serum CK-MB, cTnI at clamp off of aorta, end of operation,6hour of postoperation and 12 hour of postoperation were lower in coenzyme complex group than those in control group respectively ( all P <0.05 ) .Conclusion Coenzyme complex shows positive protection of myocardial in the VR patients.
