Effects of CRRT started at different time on patients with severe acute pancreatitis

VernacularTitle:不同时机行连续性肾替代治疗对重症急性胰腺炎疗效的影响
Author: Jianhua CAI ; Jinbo ZHANG ; Xiandan WU ; Guobin XU
Publication Type:Journal Article
Keywords: Pancreatitis; Therapies,investigational; Renal replacement therapy
From: Chinese Journal of Primary Medicine and Pharmacy 2014;(16):2406-2407
CountryChina
Language:Chinese
Abstract: Objective To explore the effects of continuous renal replacement thempy ( CRRT) on efficacy in severe acute pancreatitis ( SAP) patients based on different time .Methods A total of 38 SAP patients were divided into two groups randomly:early group(CRRT within 48h) for 21 patients and late group(CRRT after 48h)for 17 pa-tients.the APACHE II score,the length of stay ICU and the mortality of 28d were compared between the two groups . Results The APACHE Ⅱscore was significantly higher in late group than that in early group in day 1 and 2 ( t=2.231,2.304,both P<0.05);there is no significant differences between late group than that early group in APACHEⅡscore before treatment(P>0.05);the hospitalizing days and mortality were significantly higher in late group than that in early group(t=2.156,χ2 =4.293,both P<0.05);there was no significant differences between late group and early group in gender,age,APACHEⅡscore(all P>0.05).Conclusion Early CRRT can decrease both the hospi-talizing days and mortality in SAP patients .CRRT may provide more clinical benefits in the early phase (within 48h) of SAP.