The clinical study of edoravone combined with escin monosodium on acute cerebral hemorrhage
10.3760/cma.j.issn.1008-6706.2014.16.041
- VernacularTitle:依达拉奉联合七叶皂苷钠治疗急性脑出血的临床观察
- Author:
Zhen TAN
;
Youmei LYU
- Publication Type:Journal Article
- Keywords:
Hemorrhage;
Edoravone;
Escin monosodium
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(16):2491-2493
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of edoravone combined with escin monosodium on the treatment of acute cerebral hemorrhage .Methods 60 patients suffered from acute cerebral hemorrhage were randomly divided into control group and observation group .Each group had 30 patients.The control group was conventionally treated by the internal medicine .On the basis of the research on the control group ,the observation group were treated by edoravone combined with escin monosodium intravenous drip .After the treatment of 14 days,28 days,the recovery of neural function,focus volume,clinical effect were evaluated.Results Comared with the control group,after the treatment of 14 days,28 days,NIHSS score was obviously lower than that of the control group ,the difference was sig-nificant (t=2.136,t=4.117,P<0.05,P<0.01).After the treatment of 14 days,hematoma and edema of the differences were not statistically significant (t=1.395,t=0.737,all P>0.05).After the treatment of 28 days,hema-toma and edema of the differences were statistically significant (t=3.140,t=2.367,P<0.01,P<0.05).The com-parison of the clinic effect of the two groups ,the total effect was statistically significant (χ2 =6.650,P <0.01). Conclusion Edaravone combined with escin monosodium on the treatment of cerebral hemorrhage can significantly improve neurologic impairment and cerebral hematoma .Clinical effect is definite and safe .
