The clinical significance of the detection of adenosine deaminase combined with procalcitonin in adult patients with active pulmonary tuberculosis
10.3760/cma.j.issn.1008-6706.2014.16.017
- VernacularTitle:成年人活动性肺结核患者血清腺苷脱氨酶和降钙素原联合检测的临床意义
- Author:
Xiaoyan YANG
- Publication Type:Journal Article
- Keywords:
Tuberculosis,lunm;
Adenosine deaminase;
Procalcitonin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(16):2434-2435
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance of the adenosine deaminase ( ADA) and the pro-calcitonin(PCT) in adult patients with active pulmonary tuberculosis .Methods 81 patients with active pulmonary tuberculosis were enrolled into A group ,43 patients with non-tuberculous lung infection were enrolled into B group and 27 patients with lung cancer were enrolled into C group .Serum ADA and PCT were detected .Tuberculosis patients were treated for 6 months of anti-tuberculosis treatment .Results There was a significant difference between group A and B or C group about ADA (t=12.983,10.630,all P<0.01),B and C groups showed no significant difference (t=0.144,P=0.885).Group A PCT compared with group B were significantly different (t=16.775,P<0.01), the A group and C group showed no significant difference (t=1.571,P=0.119),group B compared with group C were significantly different (t=11.235,P<0.01).Tuberculosis treatment remission in 67 cases,no relief in 14 ca-ses.The levels of serum ADA and PCT in remission were significantly lower than in patients with no remission group (t=3.087,3.404,all P<0.05).Conclusion The serum ADA can be used as diagnostic indicators of active tuber-culosis,ADA and PCT joint determination can determine the prognosis of active tuberculosis .
