Data Mining of Regularities and Rules of Compound Herbal Formulae for Nonalcoholic Fatty Liver Disease

VernacularTitle:基于数据挖掘的非酒精性脂肪肝中医临床用药规律研究
Author: Huiming XU ; Yuemin WANG ; Tiansong ZHANG
Publication Type:Journal Article
Keywords: nonalcoholic fatty liver disease; data mining; compound herbal formulae; regularities and rules of prescription
From: Chinese Journal of Information on Traditional Chinese Medicine 2014;(8):38-41
CountryChina
Language:Chinese
Abstract: Objective To explore the regularities and rules of compound herbal formulae for nonalcoholic fatty liver disease (NAFLD).Methods Compound herbal formulae on NAFLD published in journals of CNKI (1979.1-2014.1), VIP (1989.1-2014.1) and CBMdisc (1979.1-2014.1) were analyzed with association rule, frequency analysis and cluster analysis.Results In 107 prescriptions, 179 herbs were involved, and frequency of usage of those herbs was 1499. A cluster analysis was used to analyze 37 herbs with high frequency (≥10) of usage, which were classified into 9 clusters including promoting circulation, clearing heat herb, diuretic herb, food stagnation herb, regulating qi herb, phlegm-resolving herb, qi tonics herb, yin-nourishing herb, qi-activating herb and purgating herb. 30 pairs of herbs and 33 rules for NAFLD were obtained by association rule analysis.Conclusion It was a point of view to understand the regularities and rules of Chinese herb prescription on NAFLD by data mining.