Advances in biomarkers of oxidative stress under sulfur mustard exposure
10.7644/j.issn.1674-9960.2014.05.000
- VernacularTitle:芥子气所致氧化应激相关生物标志物研究进展
- Author:
Yizhou MEI
;
Xiaorui ZHANG
;
Wenxia ZHOU
;
Yongxiang ZHANG
- Publication Type:Journal Article
- Keywords:
sulfur mustard;
bis (2-chloroethyl) sulfide;
biomarker;
toxic mechanism;
oxidative stress
- From:
Military Medical Sciences
2014;(5):392-395
- CountryChina
- Language:Chinese
-
Abstract:
Sulfur mustard [bis (2-chloroethyl) sulfide, sulfur mustard, SM] is considered a powerful chemical warfare agent.There is still no specific antidote due to its complex toxicological mechanism .An intimate knowledge of the toxic mechanisms and pathophysiological changes is important to the treatment of sulfur mustard injury .Oxidative stress is one of the most important pathophysiological processes involved in the toxic effect of sulfur mustard .The study of oxidative stress biomarkers induced by sulfur mustard can help to reveal the role of oxidative stress in sulfur mustard intoxication , which may contribute to better understanding of the toxic mechanism and development of therapeutic measures after sulfur mustard exposure.The research advances in oxidative stress biomarkers in sulfur mustard intoxication are reviewed .
