Efficacy of nicergoline on vascular cognitive impairment without dementia

VernacularTitle:尼麦角林治疗非痴呆型血管性认知功能障碍的疗效观察
Author: Haiyong LONG ; Shuang GUO ; Yi LI
Publication Type:Journal Article
Keywords: Cognition disorders; Nicergoline; Neuropsychological tests
From: Chinese Journal of Geriatrics 2014;33(6):598-599
CountryChina
Language:Chinese
Abstract: Objective To investigate the effect of nicergoline on cognitive ability and executive function for patients with vascular cognitive impairment without dementia (VCIND).Methods Totally 68 patients with VCIND were divided into conventional treatment group (33 cases) and nicergoline treatment group (35 cases,nicergoline 10 mg,tid added on basal conventional treatment).All of cases were continuously treated for 12 weeks.Cognitive ability and executive function before and after treatments were evaluated.Results Test scores of immediate free recall of a list of words,the numbers and symbols transformation,the word fluency,clocks and watches painting,and minimental state examination (MMSE) were significantly higher in nicergoline treatment group than in conventional treatment group (P＜0.05).Conclusions Nicergoline may improve attention and memory as well as cognitive ability in patients with vascular cognitive impairment without dementia.