Clinical observation on Jawei-Wendan decoction in treating acute exacerbation of chronic obstructive pulmonary disease (AECOPD) due to phlegm blocking in lung
10.3760/cma.j.issn.1673-4246.2014.06.007
- VernacularTitle:加味温胆汤配合常规疗法治疗痰浊积肺型慢性阻塞性肺疾病急性加重期临床研究
- Author:
Kaisheng CHEN
;
Ming LIU
;
Zhuohong WEI
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Phlegm blocking in lung;
Jawei-Wendan decoction
- From:
International Journal of Traditional Chinese Medicine
2014;(6):502-504
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the curative effects of Jawei-Wendan decoction in treating acute exacerbation of COPD due to phlegm blocking in lung. Methods From July 2010 to June 2013, 66 enrolled cases were randomly divided into a treatment group and a control group with 33 in each. Aside from receiving anti-infection and symptomatic treatment as the control group did, the treatment group was also given orally Jawei-Wendan decoction. The symptoms, pulmonary function and the variety of the laboratory indexing were observed before and after the treatment. Results ①The treatment group attained better curative effects(P<0.05) and got shorter symptomatic relief time of cough, expectoration and breathless(The T-value is respectively 16.770, 8.635, 16.762, P<0.05). ②After 7-days treatment, the cure rate of the treatment group was 63.64%, and the control group was 39.39%. Their difference was conspicuous(P<0.05). The total effective rate in treatment group was 96.97%, which was 90.91% in control group. Their difference was inconspicuous(P>0.05).③The pulmonary function indices increased significantly in the treatment group[The values of FEV1、FVC and FEV1/FVC% are (1.41±0.46)L, (2.18±0.63)L and (66.41±6.33)% before treatment, which were (2.21± 0.55)L, (2.83±0.53)L and (77.37±7.64)%after treatment, P<0.01]. A comparison of the two groups showed significant differences regarding the pulmonary function indices(P<0.05). Conclusion Jawei-Wendan decoction had good curative effect in treating acute exacerbation of COPD due to phlegm blocking in lung.
