The curative effect observation of Danhong injection combined with atorvastatin calcium in the treatment of lacunar cerebral infarction of the elderly
10.3760/cma.j.issn.1673-4246.2014.06.012
- VernacularTitle:丹红注射液联合阿托伐他汀钙治疗老年腔隙性脑梗死的临床研究
- Author:
Lin GU
;
Junjun WANG
- Publication Type:Journal Article
- Keywords:
Lacunar cerebral infarction;
Danhong injection;
Atorvastatin calcium
- From:
International Journal of Traditional Chinese Medicine
2014;(6):519-521
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical curative effect of Danhong injection combined with atorvastatin calcium in the treatment of lacunar cerebral infarction of the elderly.. Methods 125 elderly patients with lacunar cerebral infarction were randomly recruited into two groups, a control group(n=60 cases) was treated with atorvastatin calcium on the basis of conventional symptomatic treatment, and an observation group (n=65 cases) was treated with Danhong injection combined with atorvastatin calcium on the basis of conventional symptomatic treatment, the courses of two groups were 14 d. The clinical curative effect, the degree of nerve function defect score, the changes of hemorheology of two groups before and after the treatment were compared. Results The total effective rate of the observation group(89.2%)was significantly higher than that of the control group(71.7%)(P<0.05). The degree of nerve function defect score(16.24±4.63)of observation group after treatment improved significantly better than that of control group(22.17±7.38), P<0.05, and the whole blood viscosity(high), whole blood viscosity(low), plasma viscosity and fibrinogen [(3.62±0.64)mPa?s,(8.07±2.45)mPa?s, (1.61±0.30)mPa?s, (2.76±0.28)g/L]decreased significantly than that of the control group[(4.73±0.85)mPa?s, (9.86±3.26)mPa?s, (2.05±0.33)mPa?s,(3.94±0.35)g/L], P<0.05. Conclusion The treatment of Danhong injection combined with atorvastatin calcium for elderly lacunar cerebral infarction had a good therapeutic effect. It could improve nerve function defect degree and blood rheology indexes.
