MicroRNA and cancer-associated signal transduction pathways
10.3760/cma.j.issn.1673-422X.2014.06.001
- VernacularTitle:微小RNA与肿瘤信号转导通路
- Author:
Zhennan YE
;
Shanshui XU
;
Xinggen FANG
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Neoplasms;
Signal transduction
- From:
Journal of International Oncology
2014;41(6):401-404
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA (miRNA),which is closely related to the occurrence and development of tumors,may act as oncogenes or tumor suppressor genes by regulating target genes-related signal transduction pathways,such as epidermal growth factor receptor pathway,phosphatidylinositol 3-kinase-protein kinase B pathway and Ras signal transduction pathway.It is believed that miRNAs have broad application prospects in the treatment of tumors.