The value of cardiac troponin-I, B-type natriuretic peptide and blood lactic acid on evaluation of severity and prognosis in patients with septic myocardial dysfunction

VernacularTitle:肌钙蛋白-I、B型利钠肽、血乳酸对脓毒症心功能障碍患者严重程度及预后评估的价值
Author: Zhenhui ZHANG ; Lili TAO ; Weiyan CHEN ; Zixin JIANG ; Weijiang LIU
Publication Type:Journal Article
Keywords: Sepsis; Myocardial dysfunction; cTnI; BNP; Lac
From: The Journal of Practical Medicine 2014;(9):1424-1426
CountryChina
Language:Chinese
Abstract: Objective To explore the value of cardiac troponin-I (cTnI), B-type natriuretic peptide (BNP) and blood lactic acid (Lac) on evaluation of severity and prognosis in patients with septic myocardial dysfunction (SMD). Methods According to retrospective analysis of clinical data,161 cases with sepsis were divided in to SMD group and non-SMD group. And the SMD group was further divided in to death group and survival group. Blood cTnI, BNP and Lac value in each group were detected respectively. The ROC curve was used to evaluate the forecast value of cTnI, BNP and Lac on prognosis for patients. Results The value of cTnI, BNP and Lac in SMD group were significantly higher than those in non-SMD group(P<0.05);The value of cTnI, BNP and Lac in death group among the SMD patients were significantly higher than those in survival group(P<0.05);cTnI, BNP and Lac contribute to predict the 28 day mortality rate of SMD. Conclusions Blood cTnI, BNP and Lac contributes to the assessment of the severity and the prognosis of septic patients with myocardial dysfunction.