Clinical efficacy of CPAP for obstructive sleep apnea hypopnea syndrome in elderly patients
10.3969/j.issn.1006-5725.2014.09.026
- VernacularTitle:持续气道正压通气治疗老年阻塞性睡眠呼吸暂停低通气综合征的临床疗效分析
- Author:
Rui SUN
- Publication Type:Journal Article
- Keywords:
Sleep apnea,obstructive;
OSAHS;
CPAP;
Coagulation factor
- From:
The Journal of Practical Medicine
2014;(9):1427-1429
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy of continuous positive airway pressure (CPAP) with that of surgical treatment for obstructive sleep apnea-hypopnea syndrome (OSAHS) in elderly patients. Methods Seventy patients with OSAHS were divided into a study group and a control group according to different treatment methods. The study group received CPAP, while the control group underwent surgical treatment. One month after treatment, apnea-hypopnea index (AHI), lowest oxygen saturation (LSaO2), ESS scale value, coagulation factors, and platelet count were measured in both groups. Results AHI and LSaO2 were lower and ESS scale value was higher in the study group than in the control group, but with no significant differences (P>0.05). After treatment, all the indexes of coagulation factors were increased in the control group, but only plasma clotting factorⅡactivity had a significant statistical difference (P<0.05); (FⅡ: C) and (FⅧ: C) were significantly lower in the study group than in the control group (P<0.05); platelet count significantly increased in the control group (P<0.05), but markedly declined in the study group (P<0.05). Conclusions Both CPAP and surgical treatment have a better effiacy for obstructive sleep apnea-hypopnea syndrome. CPAP can more effectively improve coagulation function and lower the risks of complications.
