Clinical Observation of Zishen Tongyang Huoxue Formula Combined with Western Medicine in Treatment of Angina Pectoris Caused by Coronary Heart Disease
10.3969/j.issn.1005-5304.2014.08.007
- VernacularTitle:滋肾通阳活血方联合西药治疗冠心病心绞痛临床研究
- Author:
Ruxiu LIU
;
Liya XU
;
Jinfeng LIU
;
Jianxia TONG
;
Jing CHEN
- Publication Type:Journal Article
- Keywords:
coronary heart disease;
angina pectoris;
Zishen Tongyang Huoxue Formula;
interleukin-6;
homocysteine;
high sensitivity-C reactive protein
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(8):23-26
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of Zishen Tongyang Huoxue Formula combined with western medicine in treating angina pectoris caused by coronary heart disease (CHD).Methods Ninety patients were randomly divided into control group, TCM group and combining group, each group of 30 cases. The control group was given western medicine standardized treatment;the TCM group was treated with Zishen Tongyang Huoxue Formula only;the combining group took Zishen Tongyang Huoxue Formula and western medicine standardized treatment. The treatment course for the three groups lasted for four weeks. The clinical presentations, angina pectoris, ECG and serum biomarkers of patients in the three groups were assessed and evaluated before and after treatment.Results The clinical symptoms of TCM were significantly improved;the duration of angina was shortened;the dosage of nitroglycerin reduced after the treatment (P<0.05). The effects in the combining group was more evident compared with the other two groups (P<0.05), but there was no statistical difference between the other two groups (P>0.05). The total TCM effective rates of three groups were 83.33% (25/30), 83.33% (25/30) and 96.67% (29/30), respectively, among which the combining group was more significant (P<0.05). The total ECG effective rates of three groups were 70.00% (21/30), 76.67% (23/30) and 76.67% (23/30), respectively. Hs-CRP, IL-6 and HCY in the three groups decreased after the treatment (P<0.05). The combining group was more significant than the other two groups (P<0.05), but there was no statistical difference between the other two groups (P>0.05). Blood routine test and hepatorenal function of the three groups were all in normal range before and after treatment (P>0.05).Conclusion Using Zishen Tongyang Huoxue Formula combined with western medicinein to treat angina pectoris is effective, safe, and reliable.
