Quantitative evaluation in the stage of chronic nephrosis by shear-wave elasticity technology
10.3760/cma.j.issn.1004-4477.2014.05.011
- VernacularTitle:剪切波弹性成像技术定量评估慢性肾病分期的应用价值
- Author:
Qian WANG
;
Hong AI
;
Xixi ZHANG
;
Min DAN
;
Ning LI
;
Wenqian PAN
;
Xiaoping REN
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Nephrosis;
Shear-wave elasticity imaging
- From:Chinese Journal of Ultrasonography
2014;23(5):414-418
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of the shear-wave elasticity (SWE) imaging technology on the quantitative diagnosis of chronic nephrosis stage.Methods Sixty patients with nephrosis (nephrosis group) were evaluated with SWE and the renal function test.The Young's modulus value and the renal function were measured,and the results were compared with those of twenty healthy subjects (control group).Results Twenty cases of healthy control group were definited as R0.Sixty patients of nephrosis group were divided into four groups according to renal function:R1-R4.The Young's modulus of the nephrosis group was significantly higher than the control group (P ＜0.01).There were also statistically significant differences among each stage of the nephrosis group (except R1 and R2 of nephrosis group)(P ＜ 0.01).According the ROC curve,the cut-off value of the Young's modulus was 5.53 kPa when maximum area under the curve equal to 0.886,the sensitivity and specificity were 81.70％ and 80.40％.The Young's modulus value and renal function were positively correlated with the stage of nephrosis.The areas under the ROC curves for the Young's modulus,urea nitrogen and csytatin C were 0.965,0.950,0.965 for ≥R3,0.978,0.912,0.961 for =R4,respectively.Conclusions SWE imaging technology provided a new quantitative index for the stage of nephrosis through quantizing the elasticity of the tissue.
