Inhibitory effects of dexmedetomidine on cardiovascular responses of endotracheal intubation in chronic smokers
10.3760/cma.j.issn.1671-7368.2014.06.024
- VernacularTitle:右美托咪定抑制慢性吸烟患者气管插管反应的临床研究
- Author:
Yan XU
;
Jianqing CHENG
;
Yeying GE
;
Liyong YUAN
- Publication Type:Journal Article
- Keywords:
Dexmedetomidine;
Smoking
- From:
Chinese Journal of General Practitioners
2014;(6):499-501
- CountryChina
- Language:Chinese
-
Abstract:
From May 2012 to May 2013, 60 chronic male smokers received an intravenous infusion of dexmedetomidine 1 μg/kg (Group D, n=30) or an equal volume of normal saline (Group C, n=30) before anesthesia induction.At time of dexmedetomidine or normal saline dosing , after induction of anesthesia, 1 and 3 min after intubation, the heart rates and rate-pressure products were significantly lower in Group D than Group C ( P<0.05 ).Thus the dosing of dexmedetomidine before anesthesia induction could suppress the cardiovascular responses of endotracheal intubation in chronic smokers and avoid increasing myocardial oxygen consumption so as to protect heart functions.
