Clinical and endoscopic features of esophageal ulcers in relation to differential diagnosis of benign and malignant lesions

VernacularTitle:食管溃疡临床和内镜特点及其对良恶性鉴别的意义
Author: Hongmei YU ; Wei TAN ; Lei SHEN ; Hesheng LUO
Publication Type:Journal Article
Keywords: Esophageal; Ulcer; Endoscopy,Digestive system
From: Chinese Journal of General Practitioners 2014;(6):501-504
CountryChina
Language:Chinese
Abstract: The clinical features and endoscopic findings of 50 with esophageal ulcers were retrospectively reviewed.The ratio of male to female was 3.5∶1 (39∶11, P<0.01).The age distribution:6 cases were ≤35 y, 28 cases were 35-59 y and 16 ≥60 y ( P<0.01).Twenty nine cases were benign , 16 cases were malignant and 5 cases were uncertain.Reflux esophagitis was the main etiology of benign esophageal ulcers.The ulcers were located at upper ,middle and lower esophagus in 7, 11 and 32 cases, respectively (P<0.01).There were no significant differences of age , sex, location and amount of ulcers between benign and malignant esophageal ulcers ( P >0.05 ).However deep , large (≥2.5 cm ) and irregular esophageal ulcers were more likely to be malignant ( P <0.01 ).The clinical and endoscopic findings reveal that the malignancy of esophageal ulcer is correlated with the size , depth and shape of the lesions.