Study on General Reproductive Toxicity of Oral Administration of Pineapple Leaves Extract in Mice

VernacularTitle:新药用资源菠萝叶小鼠一般生殖毒性的研究
Author: Zhiyi YUAN ; Xi LU ; Fan LEI ; Yushuang CHAI ; Tianshi FENG ; Jingfei JIANG ; Shuang ZHAO ; Xinpei WANG ; Huiyu LI ; Dongming XING ; Lijun DU
Publication Type:Journal Article
Keywords: Pineapple leaves; medical value; reproductive toxicity; mice
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(5):966-971
CountryChina
Language:Chinese
Abstract: This article was aimed to study the general reproductive toxicity in mice in order to give a better evalua-tion of the medicinal plant of pineapple leaves (A nanas comasus L). Adult male and female mice were orally admin-istered with pineapple leaves. And then, each of the male and female mice was put together in one cage for mating. The mating success females were fed continuously. The experimental observation was conducted in pregnancy, fetal development, as well as the offspring of mice. The results showed that in addition to a large dose of pineapple leaves (4 g·kg-1) of the parental male rats having a lower body weight, pineapple leaves did not significantly affect on other parameters. There were no significant effects on pregnant mice and their offspring of mice. It was concluded that the pineapple leaves did not influence the general reproductive function of mice apparently.