Optimization of Extraction Technology of Wei-Kang Capsule by Orthogonal Test
10.11842/wst.2014.05.042
- VernacularTitle:正交试验法优选萎康胶囊提取工艺
- Author:
Ying WANG
;
Li HAN
;
Zhiye GUO
;
Limei LIU
;
Yujuan ZHANG
;
Ming YANG
- Publication Type:Journal Article
- Keywords:
Wei-Kang Capsule;
Epimedium brevicornum;
leaves of ginkgo biloba;
orthogonal test;
extraction technology
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2014;(5):1188-1192
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to optimize the extraction technology of Wei-Kang (WK) Capsule. Orthogonal test and comprehensive evaluation were used to optimize the extraction process of compound preparation. The icarrin, to-tal ginkgo flavone glycosides and the dried decocting rates were used as index components for optimizing the effect of ethanol concentration, ethanol volume, extraction duration and extraction frequency. The results showed that the opti-mal ethanol extraction technology was adding 12 times of 60% ethanol and extract for 3 times with 1 h for each ex-traction time. It was concluded that the optimized extraction technology was stable, practical, scientific and reason-able, which can be used in the large-scale industrial production.
