The comparison of clinical value of two detection methods for the detection of antithrombin Ⅲ
10.3969/j.issn.1673-4130.2014.11.039
- VernacularTitle:两种方法用于抗凝血酶Ⅲ检测的临床价值比较
- Author:
Zhi WAN
- Publication Type:Journal Article
- Keywords:
automatic coagulomete;
automatic biochemistry analyzer;
antithrombin Ⅲ;
acute myocardial infarction;
cir-rhosis
- From:
International Journal of Laboratory Medicine
2014;(11):1466-1467
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical value of automatic coagulometer and automatic biochemistry analyzer for the de-tection of antithrombin Ⅲ(AT-Ⅲ)in acute myocardial infarction and cirrhosis.Methods 55 cases of acute myocardial infarction and cirrhosis patients were investigated in the study,the healthy people was normal control.The concentration of AT-Ⅲwas detec-ted with automatic coagulometer and automatic biochemistry analyzer at the same time.Results The concentration of AT-Ⅲ detec-ted with automatic coagulometer was (251.2±58.5 )mg/L,(228.0 ±22.6)mg/L in acute myocardial infarction and cirrhosis pa-tients,the concentration of AT-Ⅲ detected with automatic biochemistry analysis was (255.6±54.3)mg/L,(230.3±23.1)mg/L in acute myocardial infarction and cirrhosis patients,and the concentration of AT-Ⅲwas significantly lower than that in normal control (P <0.05).The concentration of AT-Ⅲ detected with two detection methods in acute myocardial infarction patients was signifi-cantly lower than that in cirrhosis patients(P <0.05).There were significant difference between automatic coagulometer and auto-matic biochemistry analyzer for the detection of antithrombin Ⅲ(AT-Ⅲ).Conclusion The detection of AT-Ⅲ with automatic coag-ulometer and automatic biochemistry analyzer could diagnose and identify acute myocardial infarction and cirrhosis.