Clinical screening value of Innovance D-dimer assay in early thrombosis patients
10.3969/j.issn.1673-4130.2014.11.016
- VernacularTitle:Innovance D-dimer 试剂在血栓形成早期的筛查价值
- Author:
Mei GAO
;
Haoshan ZHANG
;
Lei ZHENG
;
Qiang LI
- Publication Type:Journal Article
- Keywords:
D-dimer;
Innovance D-dimer assay;
deep vein thrombosis
- From:
International Journal of Laboratory Medicine
2014;(11):1415-1416
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of Innovance D-dimer assay in patients with early thrombosis.Methods The D-dimer level was detected in 86 patients suspected with thrombosis and 40 healthy control subjects by using Innovance D-di-mer reagent.Results The D-dimer level was significantly higher in the case group[(4.14±7.29)mg/L]than in the control group [(0.17±0.12)mg/L],P =0.000.ROC curve analysis showed that D-dimer was a significant indicator for the clinical screening of thrombosis,and the higher D-dimer level,the greater possibility of thrombosis(AUC=0.938,P =0.000).The sensitivity,specifici-ty and negative predictive value have the satisfactory performance under the cut-off value of 0.50 mg/L.Conclusion The Innovance D-dimer is useful for excluding patients suspected with thrombosis,but it has a limited value in diagnosis of thrombosis.
