Clinical application of the procalcitonin and C reactive protein detection in the newborns with septicemia
10.3969/j.issn.1673-4130.2014.11.020
- VernacularTitle:降钙素原和C反应蛋白测定在新生儿败血症患者中的临床应用
- Author:
Jianmei LI
- Publication Type:Journal Article
- Keywords:
procalcitonin;
C reactive protein;
septicemia
- From:
International Journal of Laboratory Medicine
2014;(11):1424-1425
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical application value of procalcitonin(PCT)and C reactive protein(CRP)detection in the newborns with septicemia.Methods 50 newborns with septicemia in the hospital were enrolled as the observation group,and 50 healthy newborns at the same period were enrolled as the control group.Then the serum PCT and CRP levels and positive rates of two groups were detected and compared.The specificity,sensitivity,negative predictive values and positive predictive values of two indexes′single and combined application were analyzed,too.Results The serum PCT and CRP levels and positive rates of ob-servation group were all higher than those of control group,and the specificity and positive predictive values of two indexes′com-bined application were all higher than those of PCT and CRP single application(P <0.05).Conclusion The clinical application val-ues of PCT and CRP detection in the newborns with septicemia are high.The combined application is helpful for the early diagno-sis,it also can be as the curative effect of disease treatment effect.
