The prognosis value of galectin-3 in patients with acute ischemic stroke

VernacularTitle:半乳糖凝集素3在急性缺血性脑卒中预后评估中的价值
Author: Chunhe ZHANG ; Yan JIN ; Guijun YU ; Zengxia ZHAO
Publication Type:Journal Article
Keywords: galectin-3; acute ischemic stroke; prognosis
From: International Journal of Laboratory Medicine 2014;(11):1435-1436
CountryChina
Language:Chinese
Abstract: Objective To evaluate the prognosis value of the expression of galectin 3 in patients with acute ischemic stroke. Methods 165 Patients with acute ischemic stroke had been observated for 12 months and their occurrence of recurrent stroke e-vents were recorded.The concentration of galectin-3 was detected.Results 65 patients had recurrence stroke events with a rate of 39.39% within 12 months.It was also found that the serum concentration of galectin-3 in acute ischemic stroke recurrence patients were significantly higher than those of patients without recurrence,the difference was statistically significant(P <0.05).The rate of acute ischemic stroke recurrence in patients with high concentrations of galectin-3 was higher than that in patients with low concen-trations of galectin-3,the difference was statistically significant(P <0.05).Conclusion Galectin-3 is a good indicator to predict the prognosis of patients with acute ischemic stroke,and it could be used to evaluate the risk of recurrence in patients.