Butyl flufenamate ointment in the treatment of solar dermatitis: a clinical observation

VernacularTitle:氟芬那酸丁酯软膏治疗日光皮炎的临床观察
Author: Suqing YANG ; Yuepeng AN ; Jingdong YAN
Publication Type:Journal Article
Keywords: Sunburn; Butyl flufenamate; Clinical trials
From: Chinese Journal of Dermatology 2014;47(6):431-432
CountryChina
Language:Chinese
Abstract: Objective To evaluate the efficacy and safety of butyl flufenamate ointment for the treatment of solar dermatitis.Methods Sixty-four patients with solar dermatitis were randomly divided into the observation group (n =32) and control group (n =32) to topically apply butyl flufenamate ointment and diclofenac sodium cream,respectively,for 3 weeks.The efficacy was evaluated by lesion scores and a visual analog scale for pruritus.Results At the end of the treatment,4 patients in the observation group were clinically cured,19 markedly improved,17 improved,and 2 showed no improvement; meanwhile,2 patients in the control group were clinically cured,11 markedly improved,14 improved,and 5 showed no improvement.The total response rate was significantly higher (93.8％ vs.84.4％,P ＜ 0.05),while the pruritus score was significantly lower (P ＜ 0.05) in the observation group than in the control group.Conclusion Butyl flufenamate ointment is superior to dicofenac sodium cream in terms of both efficacy and anti-pruritic effect.