Analysis of laparoscopic myomectomy misoprostol hemostatic effect
10.3760/cma.j.issn.1008-6706.2014.14.014
- VernacularTitle:米索前列醇用于腹腔镜下子宫肌瘤剔除术止血的效果
- Author:
Lifang REN
- Publication Type:Journal Article
- Keywords:
Laparoscope;
Myomectomy;
Misoprostol
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(14):2114-2116
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore hemostatic effect of laparoscopic uterine myomectomy treated with misopr-ostol .Methods Women of childbearing age in 100 cases of laparoscopic were divided randomly according to the draw method as the control group and observation group ,each group included 50 cases.The control group were given no treatment,the observation group were given 400μg fornix misoprostol tablets about 8 hours before surgery.The op-eration time,amount of bleeding , the hospitalization time ,exhaust time,postoperative follow-up and the incidence of adverse reactions were compared between the two groups .Results (1) Operation time,amount of bleeding ,hospitali-zation time and exhaust time of the control group were (75.69 ±12.90)min,(110.37 ±43.92)mL,(7.89 ±0.29)d and (26.09 ±1.22)h,were significantly greater than those of the observation group [(61.87 ±11.06)respectively min,(72.28 ±34.52)mL,(6.38 ±0.33)d and (21.73 ±1.09)h], the difference was statistically significant (t=10.929,15.663,4.262,3.977,P=0.008,0.006,0.037,0.039);(2) Follow-up time,adverse reaction rates of control group were (10.22 ±0.90)months,24%(12/50),the observation group were (11.28 ±0.89)months,10%(5/50),there were no statistically significant differences between the two groups during the follow -up period ( t =0.189,P=0.382),but the incidence of adverse reactions compared ,the difference was statistically significant (t=6.722,P=0.015).Conclusion Hemostatic effect of laparoscopic uterine myomectomy treated with misoprostol was significant ,which is worth to be promoted and applied in clinic .