Livin and Urological Malignancy, related research and progress
- VernacularTitle:Livin 与泌尿系肿瘤的相关研究进展
- Author:
Pengcheng LI
;
Bo GE
- Publication Type:Journal Article
- Keywords:
Livin;
Inhibitor of apoptosis proteins;
Urologic neoplasms
- From:
Journal of Medical Postgraduates
2014;(7):772-776
- CountryChina
- Language:Chinese
-
Abstract:
Oncogenesis is a sophisticated process which is polygenic , multi-stage,and multi-step.Livin as an apoptosis inhibi-ting factor , is one of the members of apoptosis inhibiting factor family , it expresses highly in many tumor tissues , and is closely related to the occurrence and development of urological tumor .Tumor growth can be inhibited by interfering the expression of Livin in tumor tis-sue,which will reduce the resistance to apoptosis and increase the rate of cell apoptosis .In recent years , more and more attention was paid to the studies of Livin on gene targeting therapy .Further research of Livin might provide new ideas for the early diagnosis , clinical treatment and evaluation of prognosis of tumor .
